Based on the thinking of the construction and development of cultural and creative brand in Weishan Island, guided by the theory of cultural memory, this paper analyzes the form of cultural memory in Weishan Island, deeply excavates the cultural genes of local hometowns, summarizes the construction strategies of cultural and creative brands in Weishan Island, forms brand advantages, and promotes the high-quality development of economy, culture and society in Weishan Island, in order to provide a reference for the construction of cultural and creative brands in Weishan Island.